Is using cream-based treatment for precancerous actinic keratoses in patients who have had an organ transplant a feasible approach for future studies of squamous cell carcinoma prevention?
نویسندگان
چکیده
Abstract Linked Article: Hasan et al. Br J Dermatol 2022; 187:324–337
منابع مشابه
Use of Photodynamic Therapy for Treatment of Actinic Keratoses in Organ Transplant Recipients
Solid organ transplant recipients are predisposed to actinic keratoses (AK) and nonmelanoma skin cancers, owing to the lifelong immunosuppression required. Today, increasing numbers of organ transplants are being performed and organ transplant recipients (OTRs) are surviving much longer. Photodynamic therapy (PDT) is proving a highly effective treatment modality for AK amongst this susceptible ...
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While actinic keratoses (AKs) have a known association with cutaneous squamous cell carcinoma (SCC), the relation of actinic field change to SCC has not been quantified. This study investigated the presence of field change and AKs in renal transplant recipients (RTRs) and estimated SCC risk. In May 2010 to October 2011, a dermatologist examined 452 white RTRs (mean age 53 years) at two hospital...
متن کاملEmerging medical treatments for actinic keratoses, squamous cell carcinoma and basal cell carcinoma
Skin cancer is the most common cancer in the USA. Non-melanoma skin cancers, which include basal cell carcinoma (BCC) and squamous cell carcinoma (SCC), comprise the majority. BCC and SCC are commonly treated with surgical excision, curettage, cryotherapy and radiation. Actinic keratoses (AK) are considered precursors of SCC and are commonly treated with 5-fluorouracil, imiquimod, diclofenac, l...
متن کاملTreatment options for actinic keratoses.
Actinic keratoses are rough, scaly lesions that commonly occur on sun-exposed areas of the skin. The prevalence of the condition increases with age. Actinic keratoses are thought to be carcinomas in situ, which can progress to squamous cell carcinomas. The decision to treat can be based on cosmetic reasons; symptom relief; or, most importantly, the prevention of malignancy and metastasis. Treat...
متن کاملThe Cancer Stem Cell Hypothesis in Oral Squamous Cell Carcinoma: A New Target for the Treatment
Within a single tumor clone, cells have significantly different abilities to proliferate and form new tumors. This has led to the hypothesis that most cells in a cancer have a limited ability to divide and only a small subset of distinct cells, the cancer stem cells (CSCs), has the capacity to self-renew and form new tumors . It has been proposed that the development of tumors is based exclusiv...
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ژورنال
عنوان ژورنال: British Journal of Dermatology
سال: 2022
ISSN: ['1365-2133', '0007-0963']
DOI: https://doi.org/10.1111/bjd.21726